Abstract Inflammation in Alzheimer’s disease (AD) patients is characterized by increased cytokines and activated microglia. Epidemiological studies suggest reduced AD risk associates with long-term use of nonsteroidal anti-inflammatory drugs (NSAIDs). Whereas chronic ibuprofen suppressed inflammation and plaque-related pathology in an Alzheimer transgenic APPSw mouse model (Tg2576), excessive use of NSAIDs targeting cyclooxygenase I can cause…
RESEARCH
Curcumin Inhibits Formation of Amyloid Beta Oligomers Nov 11, 2015
Gregory M Cole talks with ScienceWatch.com and answers a few questions about this month’s Fast Moving Fronts paper in the field of Biology & Biochemistry. Article: Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and reduces amyloid in vivo Article: Curcumin inhibits formation of amyloid beta oligomers and fibrils, binds plaques, and…
Effects of Curcumin (turmeric) on Alzheimer’s Disease Nov 10, 2015
Click diagram to enlarge. Ann Indian Acad Neurol. 2008 Jan-Mar; 11(1): 13–19. doi: 10.4103/0972-2327.40220 PMCID: PMC2781139 The effect of curcumin (turmeric) on Alzheimer’s disease: An overview Shrikant Mishra and Kalpana Palanivelu Department of Neurology, VA/USC 16111, Sepulveda, CA, USA For correspondence: Shrikant Mishra, Department of Neurology, VA/USC 16111, Plummer Street, Sepulveda, CA, 91343…